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Genetics and evolution · Genetics and inheritance

Other patterns of inheritance

Before you start, make sure you know: The circulatory system (Grade 7 Science (middle school))

Mendel's model of complete dominance does not cover the whole of genetics: some flowers produce an intermediate color when crossed, some people show two alleles at once in their blood type, and some diseases affect almost only men because their gene travels on the X chromosome.

Codominance

When a pure white cow is crossed with a pure black bull, the calves are born with clearly defined white and black patches all over their bodies instead of being gray: how can two characteristics be expressed at the same time without one dominating or being diluted by the other?

Representation of codominance using two homozygous parents, red and white, and their heterozygous offspring with a patchy coat showing both colors. AA (red) BB (white) AB: patchy, not blended
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Explain what codominance is and give a human example in which two alleles are expressed simultaneously.

Explain what codominance is and give a human example in which two alleles are expressed simultaneously.

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Explain the difference between codominance and incomplete dominance, and give an example of each one.

Explain the difference between codominance and incomplete dominance, and give an example of each one.

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Incomplete dominance

If a pure red-flowered four o'clock plant is crossed with a pure white-flowered one, all the offspring produce flowers of a uniform pink shade: why does neither color dominate the other, as happened with Mendel's pea plants?

Representation of incomplete dominance using parents with red and white flowers that produce heterozygous offspring of an intermediate pink color. RR: red Rr: pink rr: white Rr × Rr gives red, pink and white again
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Explain what incomplete dominance is and describe which phenotype appears when crossing a red-flowered plant with a white-flowered plant if the trait follows this…

Explain what incomplete dominance is and describe which phenotype appears when crossing a red-flowered plant with a white-flowered plant if the trait follows this pattern.

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In the four o'clock plant, flower color shows incomplete dominance: RR is red, Rr is pink and rr is white. Cross a pink-flowered plant with a white-flowered one and…

In the four o'clock plant, flower color shows incomplete dominance: RR is red, Rr is pink and rr is white. Cross a pink-flowered plant with a white-flowered one and state the genotypic and phenotypic ratios of the offspring.

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In four o'clock plants, flower color shows incomplete dominance: red (RR), pink (Rr) and white (rr). Complete the Punnett square in the diagram, where two pink-flowered…

In four o'clock plants, flower color shows incomplete dominance: red (RR), pink (Rr) and white (rr). Complete the Punnett square in the diagram, where two pink-flowered plants are crossed, and state the genotypic and phenotypic ratios of the offspring.

Parents Rr × Rr R r R r ? ? ? ?
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Multiple alleles: the ABO blood types

At a Red Cross blood drive, donations are classified into four different blood types (A, B, AB and O), a variety that could not be explained if only two gene variants existed for this characteristic: how many different alleles actually determine blood group in the human population?

Four red blood cells with the antigens on their membrane according to blood type in the ABO system: group A with A antigens, group B with B antigens, group AB with both and group O with none, with the genotypes that give each group. Three alleles: IA, IB, i IA and IB codominant; both dominant over i A B AB O IAIA / IAi IBIB / IBi IAIB ii no antigens A antigen B antigen red blood cells seen from the front; antigens on the membrane
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A person has blood type O. State their genotype and explain whether they can have any $I^A$ or $I^B$ allele.

A person has blood type O. State their genotype and explain whether they can have any $I^A$ or $I^B$ allele.

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For the ABO blood groups there are three different alleles, but each person only has two of them. Explain what multiple allelism is and why this happens.

For the ABO blood groups there are three different alleles, but each person only has two of them. Explain what multiple allelism is and why this happens.

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Sex-linked inheritance

Sex chromosomes in metaphase: the woman has two X chromosomes and carries two alleles of an X-linked gene; the man has one X and one Y, which is much smaller and lacks that gene, so he carries only one allele. Woman (XX): two alleles Man (XY): one allele allele allele allele no copy of this gene: no allele X X X Y
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Explain what it means for a gene to be linked to the X chromosome and explain why males (XY) have only one allele for those genes, while females (XX) have two.

Explain what it means for a gene to be linked to the X chromosome and explain why males (XY) have only one allele for those genes, while females (XX) have two.

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In humans, sex is determined chromosomally: females are XX and males are XY. Explain, using the corresponding cross, why the probability of having a son or a daughter is…

In humans, sex is determined chromosomally: females are XX and males are XY. Explain, using the corresponding cross, why the probability of having a son or a daughter is equal (1:1 ratio) and which parent provides the chromosome that determines the sex of the offspring.

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Color blindness and hemophilia: "criss-cross" inheritance

Cross between a mother who is a carrier of color blindness and a father with normal vision: the parents' sex chromosomes are shown, with the maternal or paternal origin of each one, and the four possible types of children (daughter with normal vision, carrier daughter, son with normal vision and color-blind son). Carrier mother Father, normal vision XD Xd XD Y XDXD daughter normal vision XDXd daughter carrier XDY son normal vision XdY son color-blind mother's chromosome father's chromosome normal allele color blindness allele
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A color-blind man ($X^d Y$) has children with a woman with normal vision who is not a carrier ($X^D X^D$). State the genotypes and phenotypes of the sons and of the…

A color-blind man ($X^d Y$) has children with a woman with normal vision who is not a carrier ($X^D X^D$). State the genotypes and phenotypes of the sons and of the daughters, and explain why this type of inheritance is said to go "criss-cross" from fathers to daughters.

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